Diabetic ketoacidosis

 

Disease:

Cause

·     ↑Insulin resistance (illness)

·     ↓Insulin supply (first presentation, missed dose)s

Complications

·     Hypovolaemia

·     Hypertonicity

·     Hyperglycaemia

·     Electrolyte disturbance (↑Na, ↑↓K)

·     Cerebral oedema (agitation, seizure, coma)

Treatment

What:

·     Insulin

·     Saline

·     Potassium

How:

·     Rapid correction -> brain damage.

·     No boluses of insulin

·     Small boluses of saline

·     Hypertonic saline if developing cerebral oedema

Monitoring

General:

·     Vital signs and ECG

·     Conscious state

·     Urine output

Blood tests:

·     Glucose

·     Ketones

·     Acid-base

·     Electrolytes