Cerebral palsy

 

Disease:

Definition

·     Brain injury before, during or shortly after birth

·     Upper motor neuron effects are static

·     Muscle and bone effects evolve

Classification

Gross Motor Function Classification System (GMFCS)

·     From minimal impairment to wheelchair-bound

 

Human care:

Assumptions

·     Variable intellectual disability

·     Variable sensory deficit – vision, hearing

·     Good but not perfect correlation with physical abilities

->Always address both child and parent

Fear

·     Variable utility of pre-medication

o  May facilitate pre-induction vascular access

o  May delay emergence

-> Ask what works

Pain

·     Difficult to assess

-> Have plan (e.g. regional + nurse-controlled PCA)

-> Make sure devices work (e.g. epidurogram, long PIVCs)

-> Monitor by appearance / vital signs / help from parents

 

Procedures:

Airway

·     Contractures

·     Small dimensions

·     ±Bulbar palsy

·     ±GORD

-> Difficult intubation

-> Aspiration risk: suction PEG pre-op

Access

·     Atrophied limbs

·     Contractures

·     Small calibre vessels

-> Consider pre-induction vs post-induction: safety, ease, pain

-> Consider topicalization

-> Consider ultrasound

 

Drugs:

Hypnotic

·     ↓MAC -> slow wake-up

-> Fast-offset hypnotic: ***flurane

-> Fast-offset reflex suppressant: N2O, remifentanil

-> Avoid relaxant to allow titration to effect

Muscle relaxant

·     Sensitive to non-depolarising NMBD

·     Dangerous if depolarizing NMBD

-> Use rocuronium and sugammadex

-> Don’t use sux

Opioid

·     Sensitive -> sedation, respiratory depression

-> Titration to effect

-> Short-acting agent if appropriate

-> Opioid-sparing analgesia

 

General care:

Pressure care

·     Atrophied muscles

·     Spasticity and contractures

·     Osteopaenia

-> Need meticulous limb pressure care

Temperature care

·     Low metabolic rate

·     Low heat capacity

·     Cold extremities

·     Propensity for intra-op hypothermia

-> Need peri-op forced air warmer

Bowel care

·     At risk of constipation

-> Opioid-sparing analgesics

-> Pair opioids with aperients

Medication

·     Multiple comorbidities

·     Multiple medications

-> Continue all peri-op incl psychoactives and anticonvulsants

-> Avoid proconvulsants – e.g. tramadol

 

 

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