Cushing syndrome

 

Issues:

Respiratory

·     OSA

Cardiovascular

·     ↑RAAS

·     ↑Sensitivity to catecholamines

·     Volume overload

·     Hypertension

·     LVH

·     LV failure

·     Pulmonary hypertension

Metabolic

·     Hypokalaemic metabolic alkalosis (mineralocorticoid excess)

·     T2DM

·     Osteoporosis

Neuro

·     Anxiety

·     Depression

·     Psychosis

·     Insomnia

Haem/immune

·     Immunodeficiency

·     Poor wound healing

·     ↑Neutrophils, ↓lymphocytes, ↑platelets

·     (see primary exam document)

Musculoskeletal

·     Central obesity

·     Proximal myopathy

·     Moon facies

·     Bruising

 

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