Anticoagulants – neuraxial procedure:

 

 

Before

After

Aspirin

Continue

Continue

Dipyridamole

1 day

6 hours

Clopidogrel et al

7 days

No load: immediate

Load: 6 hours

Apixaban

3 days

Probably longer if kidney disease

6 hours

Rivaroxaban

3 days

Probably longer if kidney disease

6 hours

Dabigatran

3 days

5 days if kidney disease or old

Confirm with TCT (very sensitive)

6 hours

Prophylactic LMWH

12 hours (beware ↓CrCl)

12 hours

Therapeutic LMWH

1 days (beware ↓CrCl)

1 day if not high risk

2-3 days if high risk

UFH

4-6 hours (with aPTT)

1-2 hours

Warfarin

INR 1.2

Immediate

N.B. utility of Xa in assessing safety for neuraxial blockade is unknown

 

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