|
|
Definition |
Example |
|
A |
Safe |
Folate |
|
B |
Unclear – limited data in humans B1: safe in animals B2: unclear in animals B3: unsafe in animals |
Paracetamol |
|
C |
Unsafe, not teratogenic |
Most drugs |
|
D |
Unsafe, teratogenic |
Amiodarone |
|
X |
Unsafe, highly teratogenic |
Methotrexate |