2016 Heart failure with reduced ejection fraction

 

Renin-angiotensin

·      ACE

·      ARB

·      ARNI = ARB + neprilysin inhibitor

o   Entresto = valsartan + sacubitril

Beta blocker

·      Bisoprolol (B1)

·      Carvedilol (B1, B2, A1)

·      Nebivolol (B1)

·      Metoprolol XR

Mineralocorticoid receptor antagonist

·      Spironolactone

·      Eplerenone

Miscellaneous

·      HCN antagonist (ivabradine): if HR >70

·      SGLT2 inhibitor (-flozin): if T2DM

ICD

·      AICD: if LVEF <35%

·      Bi-V PPM: if LVEF <35% and very wide QRS

 

 

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