2013A14 Briefly describe the structure of mitochondria.
Outline the metabolic processes that occur in mitochondria.

· Intro

· Structure

· Functions

· Illustrations

· Intracellular organelle

· For energy production

· Abundant in metabolically active tissue

· Absent in few cells e.g. RBC

· Own DNA, maternal inheritance

Metabolic

· Oxidative phosphorylation (inner membrane)

o 36 mol ATP per molecule of glucose

· Citric acid cycle (matrix)

· β-oxidation of fatty acids (matrix)

Other

· Thermogenesis

o Uncoupling protein inserted into inner membrane

o Passage of H⁺ without ATP formation

o Only in brown fat

o Activated by adrenaline at β₃ receptor

· Apoptosis

· Calcium sequestration

· Drug biotransformation

Oxidative phosphorylation

Electron transport chain rap:

TCA cycle

β-oxidation