2013A14 Briefly describe the structure of mitochondria.
Outline the metabolic processes that occur in mitochondria.

List:

· Intro

· Structure

· Functions

· Illustrations

Intro:

· Intracellular organelle

· For energy production

· Abundant in metabolically active tissue

· Absent in few cells e.g. RBC

· Own DNA, maternal inheritance

Structure:

Functions:

Metabolic	· Oxidative phosphorylation (inner membrane) o 36 mol ATP per molecule of glucose · Citric acid cycle (matrix) · β-oxidation of fatty acids (matrix)
Other	· Thermogenesis o Uncoupling protein inserted into inner membrane o Passage of H^+ without ATP formation o Only in brown fat o Activated by adrenaline at β3 receptor · Apoptosis · Calcium sequestration · Drug biotransformation

Pathway illustration:

Oxidative phosphorylation	Electron transport chain rap: ((https://www.youtube.com/watch?v=VER6xW_r1vc)
TCA cycle
β-oxidation